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Patients on Anti-epileptic medication Long-term use of anti-epileptic medication (particularly carbamazepine, phenytoin, phenobarbital, primidone and 9 sodium valproate) is related to decreased bone mineral density that will result in osteopenia, osteoporosis, and elevated fractures in at-risk patients. Flap tension can be attributed to insufficient undermining, flap distension from edema or hematoma, or extreme rota- tional or linear development. This might go on for more than a decade, contained many of the future professors of endocrinology in London as there was no fxed senior registrar period
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